MIF-173G/C (rs755622) polymorphism as a risk factor for acute lymphoblastic leukemia development in children.

doi:10.1002/jgm.3044

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Article

MIF-173G/C (rs755622) polymorphism as a risk factor for acute lymphoblastic leukemia development in children.

The journal of gene medicine - 1 Sept 2018

Sharaf-Eldein Mohamed, Elghannam Doaa, Abdel-Malak Camelia

Abstract excerpt

BACKGROUND: Macrophage inhibitory factor (MIF) is a pro-inflammatory cytokine modulating monocyte motility and a pleiotropic regulator of different biological and cellular processes. The MIF-173G/C (rs755622) polymorphism is found in the promoter region and affects its activity. The present study investigated the MIF polymorphism as a risk factor for the development of acute lymphoblastic leukemia (ALL) in...

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PMID: 29996006
DOI: 10.1002/jgm.3044

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