Article
Serum neurofilament light chain in behavioral variant frontotemporal dementia.
Neurology - 9 Oct 2018
Steinacker Petra, Anderl-Straub Sarah, Diehl-Schmid Janine, Semler Elisa, Uttner Ingo, von Arnim Christine A F, Barthel Henryk, Danek Adrian, Fassbender Klaus, Fliessbach Klaus, Foerstl Hans, Grimmer Timo, Huppertz Hans-Jürgen, Jahn Holger, Kassubek Jan, Kornhuber Johannes, Landwehrmeyer Bernhard, Lauer Martin, Maler Juan Manuel, Mayer Benjamin, Oeckl Patrick, Prudlo Johannes, Schneider Anja, Volk Alexander E, Wiltfang Jens, Schroeter Matthias L, Ludolph Albert C, Otto Markus
Abstract excerpt
OBJECTIVE: To determine the association of serum neurofilament light chain (NfL) with functional deterioration and brain atrophy during follow-up of patients with behavioral variant frontotemporal dementia (bvFTD). METHODS: Blood NfL levels from 74 patients with bvFTD, 26 with Alzheimer disease (AD), 17 with mild cognitive impairment (MCI), and 15 healthy controls (Con) at baseline and follow-up were determined...
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