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Article

Blood-Based Biomarkers in Frontotemporal Dementia: A Narrative Review.

International journal of molecular sciences - 4 Nov 2024

Liampas Ioannis, Kyriakoulopoulou Panagiota, Karakoida Vasiliki, Kavvoura Panagiota Andriana, Sgantzos Markos, Bogdanos Dimitrios P, Stamati Polyxeni, Dardiotis Efthimios, Siokas Vasileios

Abstract excerpt

This narrative review explores the current landscape of blood biomarkers in Frontotemporal dementia (FTD). Neurofilament light chain (NfL) may be useful in the differentiation of behavioral variant FTD from primary psychiatric disorders (PPDs) or dementia with Lewy bodies (DLB). In prodromal FTD and presymptomatic mutation carriers (GRN, MAPT, C9orf72), elevated NfL may herald pheno-conversion to full-blown...

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PMID: 39519389
DOI: 10.3390/ijms252111838
PMCID: PMC11546606

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