Article

Cerebrospinal fluid neurofilament light chain differentiates behavioural variant frontotemporal dementia progressors from ‘phenocopy’ non-progressors

2022-01-15

Abstract excerpt

<h4>Background</h4> Distinguishing behavioural variant frontotemporal dementia (bvFTD) from non-neurodegenerative ‘non-progressor’, ‘phenocopy’ mimics of frontal lobe dysfunction, can be one of the most challenging clinical dilemmas. A biomarker of neuronal injury, neurofilament light chain (NfL), could reduce misdiagnosis and delay. <h4>Methods</h4> Cerebrospinal fluid (CSF) NfL, amyloid beta 1-42 (AB42), total a...

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Literature Corpus work: fecb0650-c2d0-5972-869d-302432b66ec8
DOI: 10.1101/2022.01.14.22269323

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