Article
Cancer Cell Metabolism Featuring Nrf2.
Current drug discovery technologies - 1 Jan 2020
Chatterjee Payal, Yadav Mukesh, Chauhan Namrata, Huang Ying, Luo Yun
Abstract excerpt
Although the major role of Nrf2 has long been established as a transcription factor for providing cellular protection against oxidative stress, multiple pieces of research and reviews now claim exactly the opposite. The dilemma - "to activate or inhibit" the protein requires an immediate answer, which evidently links cellular metabolism to the causes and purpose of cancer. Profusely growing cancerous cells have...
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