Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple Mechanisms Inactivate the LIN-41 RNA-Binding Protein To Ensure a Robust Oocyte-to-Embryo Transition in Caenorhabditis elegans.

Genetics - 1 Nov 2018

Spike Caroline A, Huelgas-Morales Gabriela, Tsukamoto Tatsuya, Greenstein David

Abstract excerpt

In the nematode Caenorhabditis elegans, the conserved LIN-41 RNA-binding protein is a translational repressor that coordinately controls oocyte growth and meiotic maturation. LIN-41 exerts these effects, at least in part, by preventing the premature activation of the cyclin-dependent kinase CDK-1 Here we investigate the mechanism by which LIN-41 is rapidly eliminated upon the onset of meiotic maturation....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Embryo, Nonmammalian

Share to Gene Editing

Share to Meiosis

Share to Oocytes

Share to Protein Domains

Share to Proteolysis

Source

Open in PubMed Open full text

Identifiers

PMID: 30206186
DOI: 10.1534/genetics.118.301421
PMCID: PMC6218228

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple Mechanisms Inactivate the LIN-41 RNA-Binding Protein To Ensure a Robust Oocyte-to-Embryo Transition in Caenorhabditis elegans.PMID 30206186Read ↗

The TRIM-NHL protein LIN-41 controls the onset of developmental plasticity in Caenorhabditis elegans.Semantic proximity Read ↗

The TRIM-NHL protein LIN-41 and the OMA RNA-binding proteins antagonistically control the prophase-to-metaphase transition and growth of Caenorhabditis elegans oocytes.Semantic proximity Read ↗

GLD-1, a Cytoplasmic Protein Essential for Oocyte Differentiation, Shows Stage- and Sex-Specific Expression duringCaenorhabditis elegansGermline DevelopmentSemantic proximity Read ↗

GLS-1, a novel P granule component, modulates a network of conserved RNA regulators to influence germ cell fate decisions.Semantic proximity Read ↗

<i>C. elegans</i> LIN-28 controls temporal cell-fate progression by regulating LIN-46 expression via the 5’UTR of <i>lin-46</i> mRNASemantic proximity Read ↗

The Ubiquitin-Proteasome Pathway Mediates Selective Degradation of Unloaded Argonautes in <i>C. elegans</i>Semantic proximity Read ↗

Germline Blastomeres transcriptomics in the presence or absence of PIE-1 during <i>C. elegans</i> early embryogenesisSemantic proximity Read ↗

C. elegans LIN-28 controls temporal cell fate progression by regulating LIN-46 expression via the 5' UTR of lin-46 mRNA.Semantic proximity Read ↗

An RNAi-based suppressor screen identifies interactors of the Myt1 ortholog of Caenorhabditis elegans.Semantic proximity Read ↗

let-7 miRNA and lin-46 mRNA are essential targets of the LIN28 RNA-binding protein in Caenorhabditis elegans developmental timing regulation.Semantic proximity Read ↗

The adaptor-like protein ROG-1 is required for activation of the Ras-MAP kinase pathway and meiotic cell cycle progression in Caenorhabditis elegans.Semantic proximity Read ↗

The Caenorhabditis elegans heterochronic gene lin-14 coordinates temporal progression and maturation in the egg-laying system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.