Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The TRIM-NHL protein LIN-41 controls the onset of developmental plasticity in Caenorhabditis elegans.

PLoS genetics - 1 Aug 2014

Tocchini Cristina, Keusch Jeremy J, Miller Sarah B, Finger Susanne, Gut Heinz, Stadler Michael B, Ciosk Rafal

Abstract excerpt

The mechanisms controlling cell fate determination and reprogramming are fundamental for development. A profound reprogramming, allowing the production of pluripotent cells in early embryos, takes place during the oocyte-to-embryo transition. To understand how the oocyte reprogramming potential is controlled, we sought Caenorhabditis elegans mutants in which embryonic transcription is initiated precociously in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cellular Reprogramming

Share to Embryo, Nonmammalian

Share to Embryonic Development

Share to Germ Cells

Share to Oocytes

Share to Ubiquitin-Protein Ligases

Source

Open in PubMed Open full text

Identifiers

PMID: 25167051
DOI: 10.1371/journal.pgen.1004533
PMCID: PMC4148191

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The TRIM-NHL protein LIN-41 controls the onset of developmental plasticity in Caenorhabditis elegans.PMID 25167051Read ↗

The TRIM-NHL protein LIN-41 and the OMA RNA-binding proteins antagonistically control the prophase-to-metaphase transition and growth of Caenorhabditis elegans oocytes.Semantic proximity Read ↗

Multiple Mechanisms Inactivate the LIN-41 RNA-Binding Protein To Ensure a Robust Oocyte-to-Embryo Transition in Caenorhabditis elegans.Semantic proximity Read ↗

Germline Blastomeres transcriptomics in the presence or absence of PIE-1 during <i>C. elegans</i> early embryogenesisSemantic proximity Read ↗

Cell-Specific mRNA Profiling of the Caenorhabditis elegans Somatic Gonadal Precursor Cells Identifies Suites of Sex-Biased and Gonad-Enriched Transcripts.Semantic proximity Read ↗

Novel gain-of-function alleles demonstrate a role for the heterochronic gene lin-41 in C. elegans male tail tip morphogenesis.Semantic proximity Read ↗

<i>let-7</i> controls the transition to adulthood by releasing select transcriptional regulators from repression by LIN41Semantic proximity Read ↗

Epigenetic dynamics during germline development: insights from Drosophila and C. elegansSemantic proximity Read ↗

The TRIM-NHL protein NHL-2 is a Novel Co-Factor of the CSR-1 and HRDE-1 22G-RNA PathwaysSemantic proximity Read ↗

<i>C. elegans</i> LIN-28 controls temporal cell-fate progression by regulating LIN-46 expression via the 5’UTR of <i>lin-46</i> mRNASemantic proximity Read ↗

The adaptor-like protein ROG-1 is required for activation of the Ras-MAP kinase pathway and meiotic cell cycle progression in Caenorhabditis elegans.Semantic proximity Read ↗

Competence for chemical reprogramming of sexual fate correlates with an intersexual molecular signature in Caenorhabditis elegans.Semantic proximity Read ↗

PBRM-1/PBAF-regulated genes in a multipotent progenitorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.