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Proteomic landscape of Alzheimer’s disease: emerging technologies, advances and insights (2021 – 2025)

14 Jul 2025

Abstract excerpt

The advancements of proteomics technologies are shaping Alzheimer's disease (AD) research, revealing new molecular insights and improving biomarker discovery. Here, we summarize major AD proteomics studies since our 2021 review, focusing on disease mechanisms and biomarker identification. Enhanced sensitivity and throughput in proteome profiling have been driven by mass spectrometry (MS)-based approaches and...

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PMID: 40660303
DOI: 10.1186/s13024-025-00874-5

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