Article
PancanQTL: systematic identification of cis-eQTLs and trans-eQTLs in 33 cancer types.
Nucleic acids research - 4 Jan 2018
Gong Jing, Mei Shufang, Liu Chunjie, Xiang Yu, Ye Youqiong, Zhang Zhao, Feng Jing, Liu Renyan, Diao Lixia, Guo An-Yuan, Miao Xiaoping, Han Leng
Abstract excerpt
Expression quantitative trait locus (eQTL) analysis, which links variations in gene expression to genotypes, is essential to understanding gene regulation and to interpreting disease-associated loci. Currently identified eQTLs are mainly in samples of blood and other normal tissues. However, no database comprehensively provides eQTLs in large number of cancer samples. Using the genotype and expression data of...
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