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Article

Large-scale meta-analysis highlights the hypothalamic-pituitary-gonadal axis in the genetic regulation of menstrual cycle length.

Human molecular genetics - 15 Dec 2018

Laisk Triin, Kukuškina Viktorija, Palmer Duncan, Laber Samantha, Chen Chia-Yen, Ferreira Teresa, Rahmioglu Nilufer, Zondervan Krina, Becker Christian, Smoller Jordan W, Lippincott Margaret, Salumets Andres, Granne Ingrid, Seminara Stephanie, Neale Benjamin, Mägi Reedik, Lindgren Cecilia M

Abstract excerpt

The normal menstrual cycle requires a delicate interplay between the hypothalamus, pituitary and ovary. Therefore, its length is an important indicator of female reproductive health. Menstrual cycle length has been shown to be partially controlled by genetic factors, especially in the follicle-stimulating hormone beta-subunit (FSHB) locus. A genome-wide association study meta-analysis of menstrual cycle length in...

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Identifiers

PMID: 30202859
DOI: 10.1093/hmg/ddy317
PMCID: PMC6276838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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