Article
The polymorphic insertion of the luteinizing hormone receptor "insLQ" show a negative association to LHR gene expression and to the follicular fluid hormonal profile in human small antral follicles.
Molecular and cellular endocrinology - 15 Jan 2018
Borgbo T, Chrudimska J, Macek M, Jeppesen J V, Bøtkjær J A, Kristensen S G, Macklon K T, Ernst E, Hansen L L, Yding Andersen C
Abstract excerpt
The luteinizing hormone receptor (LHCGR) has a little studied polymorphic 6 bp insertion (rs4539842/insLQ). This study has evaluated the insLQ polymorphism in relation to potential associations with hormonal characteristics of human small antral follicles (hSAFs). In total, 310 hSAFs were collected from 86 women undergoing fertility preservation. Analysis included hormonal profile of 297 follicular fluid (FF)...
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