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Pancreatic Exocrine Tissue Architecture and Integrity are Maintained by E-cadherin During Postnatal Development

3 Sept 2018

Abstract excerpt

Abstract Cadherin-mediated cell-cell adhesion plays an important role in organ development and changes in cadherin expression are often linked to morphogenetic and pathogenic events. Cadherins interact with other intracellular components to form adherens junctions (AJs) and provide mechanical attachments between adjacent cells. E-cadherin (Cdh1) represents an integral component of these intercellular junctions....

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PMID: 30194315
DOI: 10.1038/s41598-018-31603-2

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