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Article

Pancreas-specific deletion of Prox1 affects development and disrupts homeostasis of the exocrine pancreas.

Gastroenterology - 1 Apr 2012

Westmoreland Joby J, Kilic Gamze, Sartain Caroline, Sirma Sema, Blain Jennifer, Rehg Jerold, Harvey Natasha, Sosa-Pineda Beatriz

Abstract excerpt

BACKGROUND & AIMS: The exocrine portion of the pancreas functions in digestion and preserves pancreatic homeostasis. Learning how this tissue forms during embryogenesis could improve our understanding of human pancreatic diseases. Expression of the homeobox gene Prox1 in the exocrine pancreas changes throughout development in mice. We investigated the role of Prox1 in development of the exocrine pancreas in mice....

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Identifiers

PMID: 22178591
DOI: 10.1053/j.gastro.2011.12.007
PMCID: PMC3398795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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