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Article

Wnt/β-catenin signaling is required for development of the exocrine pancreas

12 Jan 2007

Abstract excerpt

BACKGROUND: Beta-catenin is an essential mediator of canonical Wnt signaling and a central component of the cadherin-catenin epithelial adhesion complex. Dysregulation of beta-catenin expression has been described in pancreatic neoplasia. Newly published studies have suggested that beta-catenin is critical for normal pancreatic development although these reports reached somewhat different conclusions. In...

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PMID: 17222338
DOI: 10.1186/1471-213x-7-4

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