Article
Dorsal pancreas agenesis in N-cadherin- deficient mice.
Developmental biology - 1 Oct 2001
Esni F, Johansson B R, Radice G L, Semb H
Abstract excerpt
Members of the cadherin family of cell adhesion molecules are thought to be crucial regulators of tissue patterning and organogenesis. During pancreatic ontogeny N-cadherin is initially expressed in the pancreatic mesenchyme and later in pancreatic endoderm. Analysis of N-cadherin-deficient mice revealed that these mice suffer from selective agenesis of the dorsal pancreas. Further analysis demonstrated that the...
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