Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cross-tissue eQTL enrichment of associations in schizophrenia.

PloS one - 1 Jan 2018

Bettella Francesco, Brown Andrew A, Smeland Olav B, Wang Yunpeng, Witoelar Aree, Buil Demur Alfonso A, Thompson Wesley K, Zuber Verena, Dale Anders M, Djurovic Srdjan, Andreassen Ole A

Abstract excerpt

The genome-wide association study of the Psychiatric Genomics Consortium identified over one hundred schizophrenia susceptibility loci. The number of non-coding variants discovered suggests that gene regulation could mediate the effect of these variants on disease. Expression quantitative trait loci (eQTLs) contribute to variation in levels of mRNA. Given the co-occurrence of schizophrenia and several traits not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Blood Chemical Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to Epidermis

Share to Gene Expression Regulation

Share to Organ Specificity

Share to Quantitative Trait Loci

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 30188921
DOI: 10.1371/journal.pone.0202812
PMCID: PMC6126834

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cross-tissue eQTL enrichment of associations in schizophrenia.PMID 30188921Read ↗

Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue.Semantic proximity Read ↗

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.Semantic proximity Read ↗

Transcriptome-wide association studies: opportunities and challengesSemantic proximity Read ↗

Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortexSemantic proximity Read ↗

Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes.Semantic proximity Read ↗

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell typesSemantic proximity Read ↗

Stratified Linkage Disequilibrium Score Regression reveals enrichment of eQTL effects on complex traits is not tissue specificSemantic proximity Read ↗

Joint-Tissue Integrative Analysis Identified Hundreds of Schizophrenia Risk Genes.Semantic proximity Read ↗

Identification of Brain Expression Quantitative Trait Loci Associated with Schizophrenia and Affective Disorders in Normal Brain TissueSemantic proximity Read ↗

Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression.Semantic proximity Read ↗

A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci.Semantic proximity Read ↗

Comprehensive evaluation of disease- and trait-specific enrichment for eight functional elements among GWAS-identified variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.