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The annulus: composition, role and importance in sperm flagellum biogenesis and male fertility

15 Dec 2024

Abstract excerpt

The annulus is an electron-dense ring structure that surrounds the axoneme and compartmentalizes the sperm flagellum into two parts: the midpiece and the principal piece. The function of the annulus as a diffusion barrier in the mature spermatozoon is now well described but its function during spermiogenesis remains unclear. The intriguing spatio-temporal dynamics of the annulus during spermiogenesis and its...

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PMID: 39676174
DOI: 10.1186/s12610-024-00241-2

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