Article

CFAP61 is required for sperm flagellum formation and male fertility in human and mouse

2021-03-06

Abstract excerpt

Defects in the structure or motility of cilia and flagella may lead to severe diseases such as primary ciliary dyskinesia (PCD), a multisystemic disorder with heterogeneous manifestations affecting primarily respiratory and reproductive functions. We report that CFAP61 is a conserved component of the Calmodulin and radial Spoke associated Complex (CSC) of cilia. We find that a CFAP61 splice variant, c.143+5G>A, ca...

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Identifiers and source

Literature Corpus work: 55a05943-2168-5c47-813b-d4071ca4d1eb
DOI: 10.1101/2021.03.04.433881

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