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Article

Haplotype Based Analysis of XRCC3 Gene Polymorphisms in Thyroid Cancer.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2017

Sarwar Romana, Mahjabeen Ishrat, Bashir Kashif, Saeed Soma, Kayani Mahmood Akhtar

Abstract excerpt

BACKGROUND/AIMS: In mammalian cells, XRCC3 plays an important role in the DNA double-strand breaks (DSBs) repair by homologous recombination. Genetic polymorphisms in XRCC3 gene may potentially affect the repair of DSBs and thus confer susceptibility to thyroid cancer. In this study, we used a haplotype-based approach to investigate whether 5 selected SNPs i.e. rs1799796, rs1799794, rs861539, rs709399 and...

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Source

Identifiers

PMID: 28490032
DOI: 10.1159/000477109

Genes

XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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