Article
HLA class II alleles differing by a single amino acid associate with clinical phenotype and outcome in patients with primary membranous nephropathy.
Kidney international - 1 Nov 2018
Wang Huai-Yu, Cui Zhao, Xie Li-Jun, Zhang Li-Jie, Pei Zhi-Yong, Chen Fang-Jin, Qu Zhen, Huang Jing, Zhang Yi-Miao, Wang Xin, Wang Fang, Meng Li-Qiang, Cheng Xu-Yang, Liu Gang, Zhou Xu-Jie, Zhang Hong, Debiec Hanna, Ronco Pierre, Zhao Ming-Hui
Abstract excerpt
Genome-wide associations and HLA genotyping have revealed associations between HLA alleles and susceptibility to primary membranous nephropathy. However, associations with clinical phenotypes and kidney outcome are poorly defined. We previously identified DRB1*1501 and DRB1*0301 as independent risk alleles for primary membranous nephropathy. Here, we investigated HLA associations with demographic characteristics,...
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