Article
Comprehensive assessment of the association between genes on JAK-STAT pathway (IFIH1, TYK2, IL-10) and systemic lupus erythematosus: a meta-analysis.
Archives of dermatological research - 1 Nov 2018
Yin Qiong, Wu Liang-Cai, Zheng Lu, Han Ming-Yu, Hu Li-Ya, Zhao Pian-Pian, Bai Wei-Yang, Zhu Xiao-Wei, Xia Jiang-Wei, Wang Xiao-Bo, Zhang Xing-Wei, Zheng Hou-Feng
Abstract excerpt
Previous studies have reported that genes relating to JAK-STAT pathway (IFIH1, TYK2 and IL-10) conferred the susceptibility to SLE. In this study, we performed a meta-analysis (including 43 studies) to evaluate the association between IFIH1 (9288 patients and 24,040 controls), TYK2 (4928 patients and 11,536 controls), IL-10 (3623 patients and 4907 controls) polymorphisms and systemic lupus erythematosus (SLE) in...
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