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Article

Genetic association and interaction between the IRF5 and TYK2 genes and systemic lupus erythematosus in the Han Chinese population.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Oct 2015

Tang Liang, Wan Pengcheng, Wang Yong, Pan Jiabao, Wang Yan, Chen Bifeng

Abstract excerpt

OBJECTIVES: The purpose of this case-control study was to investigate whether polymorphisms and gene-gene interactions of the two type I interferon (IFN) genes (IRF5 and TYK2) are the susceptible factors of systemic Lupus erythematosus (SLE) in the Han Chinese population. METHODS: The four variants [rs2004640, rs2070197, rs10954213 and exon6 insertion/deletion (in/de)] of IRF5 gene and five single-nucleotide...

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Identifiers

PMID: 26294277
DOI: 10.1007/s00011-015-0865-2

Genes

TYK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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