Article
Meta-analysis of TYK2 gene polymorphisms association with susceptibility to autoimmune and inflammatory diseases.
Molecular biology reports - 1 Oct 2011
Tao Jin-Hui, Zou Yan-Feng, Feng Xiao-Liang, Li Jing, Wang Fang, Pan Fan-Ming, Ye Dong-Qing
Abstract excerpt
The aim of our meta-analysis was to quantitatively summarize the association of TYK2 gene polymorphisms with autoimmune and inflammatory diseases. 11 studies that included data from 21497 cases and 22647 controls were identified. OR was used as a measure of the effect of the association in a fixed/random effect model. Meta-analysis was performed for six TYK2 gene polymorphisms (rs34536443, rs2304256, rs280523,...
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