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Associations between RAD51D germline mutations and breast cancer risk and survival in BRCA1/2-negative breast cancers

23 Aug 2018

Abstract excerpt

Background: RAD51D is involved in DNA double-strand break repair by homologous recombination and plays an important role in the maintenance of genomic stability. The associations between RAD51D germline mutations and breast cancer risk and survival are not fully elucidated. Patients and methods: RAD51D germline mutations were determined using a multigene panel in 7657 unselected breast cancer patients who were...

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PMID: 30165555
DOI: 10.1093/annonc/mdy338

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