Article
Polymorphic Variants in 5'-UTR Regions of the RAD51 Gene are Associated With RAD51 Expression and Triple-Negative Breast Cancer (TNBC): A Case-Control Study.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Apr 2021
Al Hamad Mohammad, Kussaibi Haitham, Alkharsah Khaled R, Alsayyah Ahmed, El Shawarby Mohammed, Al Tamimi Dalal, Alomari Munther, Bakshi Hamid A, Tambuwala Murtaza M, Al Zoubi Mazhar S
Abstract excerpt
Breast cancer is a heterogeneous disease at morphologic and molecular levels, which is considered the most commonly occurring cancer in women. RAD51, a DNA-repairing protein, involves homologous recombination and has a vital role in genome stability. Polymorphism of the RAD51 gene, and its overexpression, has been proposed to be associated with the development of breast cancer. Overexpression of RAD51 in many...
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