Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In vivo evolution of drug-resistant Mycobacterium tuberculosis in patients during long-term treatment.

BMC genomics - 29 Aug 2018

Xu Yuhui, Liu Fei, Chen Suting, Wu Jiannan, Hu Yongfei, Zhu Baoli, Sun Zhaogang

Abstract excerpt

BACKGROUND: In the current scenario, the drug-resistant tuberculosis is a significant challenge in the control of tuberculosis worldwide. In order to investigate the in vivo evolution of drug-resistant M. tuberculosis, the present study envisaged sequencing of the draft genomes of 18 serial isolates from four pre-extensively drug-resistant (pre-XDR) tuberculosis patients for continuous genetic alterations....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antitubercular Agents
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Microbial Sensitivity Tests

Share to Mycobacterium tuberculosis

Share to Polymorphism, Single Nucleotide

Share to Time Factors

Share to Tuberculosis, Multidrug-Resistant

Source

Open in PubMed Open full text

Identifiers

PMID: 30157763
DOI: 10.1186/s12864-018-5010-5
PMCID: PMC6116439

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In vivo evolution of drug-resistant Mycobacterium tuberculosis in patients during long-term treatment.PMID 30157763Read ↗

Evolution of Drug-Resistant Mycobacterium tuberculosis Strains and Their Adaptation to the Human Lung EnvironmentSemantic proximity Read ↗

Dynamics of Extensive Drug Resistance Evolution of Mycobacterium tuberculosis in a Single Patient During 9 Years of Disease and Treatment.Semantic proximity Read ↗

Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients.Semantic proximity Read ↗

In Host Mutational Adaptation of Mycobacterium Tuberculosis Complex Strains During Tuberculosis Infection.Semantic proximity Read ↗

Long-term spatiotemporal evolution of drug-resistant Mycobacterium tuberculosis in China.Semantic proximity Read ↗

Emergence and evolution of drug-resistant Mycobacterium tuberculosis in eastern China: A six-year prospective study.Semantic proximity Read ↗

Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient.Semantic proximity Read ↗

Mycobacterium tuberculosis Intra-Host Evolution Among Drug-Resistant Tuberculosis Patients Failing TreatmentSemantic proximity Read ↗

Evolution of Mycobacterium tuberculosis drug resistance in the genomic era.Semantic proximity Read ↗

Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized careSemantic proximity Read ↗

Uncovering resistance pathways to first- and last-line antibiotics in Mycobacterium tuberculosis populations.Semantic proximity Read ↗

Evolution of Mycobacterium tuberculosis : New Insights into Pathogenicity and Drug ResistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.