Article
Emergence and evolution of drug-resistant Mycobacterium tuberculosis in eastern China: A six-year prospective study.
Genomics - 1 May 2023
Wang Luqi, Chen Bin, Zhou Hui, Mathema Barun, Chen Liang, Li Xiangchen, Lu Yewei, Liu Zhengwei, Wang Xiaomeng, Wang Weibing
Abstract excerpt
Understanding the emergence and evolution of drug resistance can inform public health intervention to combat tuberculosis (TB). In this prospective molecular epidemiological surveillance study from 2015 to 2021 in eastern China, we prospectively collected whole-genome sequencing and epidemiological data on TB patients. We dissect the ordering of drug resistance mutation acquisition for nine commonly used anti-TB...
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