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Article

Interferon Regulatory Factor 9 Structure and Regulation

10 Aug 2018

Abstract excerpt

Interferon regulatory factor 9 (IRF9) is an integral transcription factor in mediating the type I interferon antiviral response, as part of the interferon-stimulated gene factor 3. However, the role of IRF9 in many important non-communicable diseases has just begun to emerge. The duality of IRF9's role in conferring protection but at the same time exacerbates diseases is certainly puzzling. The regulation of IRF9...

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PMID: 30147694
DOI: 10.3389/fimmu.2018.01831

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