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Article

IRF5-mediated immune responses and its implications in immunological disorders

9 Jul 2018

Abstract excerpt

Transcription factors are gene regulators that activate or repress target genes. One family of the transcription factors that have been extensively studied for their crucial role in regulating gene network in the immune system is the interferon regulatory factors (IRFs). IRFs possess a novel turn-helix turn motif that recognizes a specific DNA consensus found in the promoters of many genes that are involved in...

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PMID: 29985675
DOI: 10.1080/08830185.2018.1469629

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