Article
Evaluation of the impact of CYP1A2 induction by charbroiled meal on metabolic phenotype.
Clinical nutrition ESPEN - 1 Oct 2018
Anumu George Joseph, Adehin Ayorinde, Bolaji Oluseye O
Abstract excerpt
BACKGROUND & AIMS: The process of grilling food items often generates polycyclic aromatic hydrocarbons which are established inducers of CYP1A2, a human drug metabolising enzyme, known to activate some procarcinogens. The impact of such induction on CYP1A2 metabolic phenotype has been the subject of some discordant findings. This study, while considering some limitations in previous study designs, evaluated the...
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