Article
KMT2A-rearranged infantile acute myeloid leukemia masquerading as juvenile myelomonocytic leukemia.
International journal of hematology - 1 Dec 2018
Kanayama Takuyo, Imamura Toshihiko, Kawabe Yasuhiro, Osone Shinya, Tahara Junko, Iwasaki Fuminori, Miyagawa Naoyuki, Goto Hiroaki, Imashuku Shinsaku, Hosoi Hajime
Abstract excerpt
Mixed lineage leukemia [MLL; now known as lysine methyltransferase 2A (KMT2A)] rearrangement-positive acute myeloid leukemia (AML) and juvenile myelomonocytic leukemia (JMML) are distinct diseases, although age of susceptibility (infancy or early childhood) and abnormal monocytosis are common clinical features. Here, we report two cases of KMT2A-rearranged infantile AML masquerading as JMML at initial...
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