Article

Multiple Lineage Switches in KMT2A Rearranged Infant Leukemia, Responsive to Combination Therapy with CPX-351 and Inotuzumab

2023-08-07

Abstract excerpt

Rearrangements of the KMT2A gene are characteristic of infantile acute lymphoblastic leukemia (ALL) and are associated with increased lineage plasticity and resistance to therapy. Here, we describe the case of a 9-month-old infant with infantile ALL who experienced multiple immunophenotypic switches in her leukemia throughout therapy and ultimately achieved remission with the combination of CPX-351 and Inotuzumab...

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Literature Corpus work: 44676e0c-51ed-5cec-a8d8-67c9f489c64d
DOI: 10.22541/au.169140970.02716723/v1

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