Article
The effects of human leukocyte antigen DRB1*13 and apolipoprotein E on age-related variability of synchronous neural interactions in healthy women.
EBioMedicine - 1 Sept 2018
James Lisa M, Dolan Stacy, Leuthold Arthur C, Engdahl Brian E, Georgopoulos Angeliki, Georgopoulos Apostolos P
Abstract excerpt
BACKGROUND: Age-related brain changes are well-documented and influenced by genetics. Extensive research links apolipoprotein E (apoE) to brain function, with the E4 allele serving as a risk factor for brain disease, including Alzheimer's disease, and the E2 allele conferring protection. Recent evidence also supports protective effects of another gene, human leukocyte antigen (HLA) DRB1*13, on brain disease and...
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