A positive association between phosphorylated Tau217 (pTau217) and neural correlations is prevented by human leukocyte antigen allele DRB1*13:01.

Abstract excerpt

Subtle deviations in zero-lag cross correlations (synchronous neural interactions, SNI) differentiate healthy from pathological brain states. Here, we assessed blood biomarkers of dementia and neurodegeneration in relation to SNI in 175 women participating in a longitudinal study for a total of 348 acquisitions. Of seven biomarkers tested (Aβ1-40, Aβ1-42, Aβ1-42/Aβ1-40 ratio, neurofilament light chain [NFL],...

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