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BRCAness and prostate cancer: diagnostic and therapeutic considerations.

Prostate cancer and prostatic diseases - 1 Nov 2018

Dhawan Mallika, Ryan Charles J

Abstract excerpt

BACKGROUND: Recent advances in genetic sequencing and recent studies focusing on the broader use of Poly ADP Ribose polymerase (PARP) inhibitors have led to an upsurge of interest in DNA repair mutations as they relate to prostate cancer. METHODS: This review outlines ongoing studies and recent publications as they relate to the prevalence and detection of DNA repair mutations in metastatic prostate cancer. The...

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Identifiers

PMID: 30131605
DOI: 10.1038/s41391-018-0069-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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