Genetic Regulation of the Thymic Stromal Lymphopoietin (TSLP)/TSLP Receptor (TSLPR) Gene Expression and Influence of Epistatic Interactions Between IL-33 and the TSLP/TSLPR Axis on Risk of Coronary Artery Disease.

doi:10.3389/fimmu.2018.01775

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Genetic Regulation of the Thymic Stromal Lymphopoietin (TSLP)/TSLP Receptor (TSLPR) Gene Expression and Influence of Epistatic Interactions Between IL-33 and the TSLP/TSLPR Axis on Risk of Coronary Artery Disease.

Frontiers in immunology - 1 Jan 2018

Nie Shao-Fang, Zha Ling-Feng, Fan Qian, Liao Yu-Hua, Zhang Hong-Song, Chen Qian-Wen, Wang Fan, Tang Ting-Ting, Xia Ni, Xu Cheng-Qi, Zhang Jiao-Yue, Lu Yu-Zhi, Zeng Zhi-Peng, Jiao Jiao, Li Yuan-Yuan, Xie Tian, Zhang Wen-Juan, Wang Dan, Wang Chu-Chu, Fa Jing-Jing, Xiong Hong-Bo, Ye Jian, Yang Qing, Wang Peng-Yun, Tian Sheng-Hua, Lv Qiu-Lun, Li Qing-Xian, Qian Jin, Li Bin, Wu Gang, Wu Yan-Xia, Yang Yan, Yang Xiang-Ping, Hu Yu, Wang Qing K, Cheng Xiang, Tu Xin

Abstract excerpt

The thymic stromal lymphopoietin (TSLP)/TSLP receptor (TSLPR) axis is involved in multiple inflammatory immune diseases, including coronary artery disease (CAD). To explore the causal relationship between this axis and CAD, we performed a three-stage case-control association analysis with 3,628 CAD cases and 3,776 controls using common variants in the genes TSLP, interleukin 7 receptor (IL7R), and TSLPR. Three...

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PMID: 30123216
DOI: 10.3389/fimmu.2018.01775
PMCID: PMC6085432

Genes

TSLP
CAD

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