Article
Polymorphism of stromal cell-derived factor-1 selectively upregulates gene expression and is associated with increased susceptibility to coronary artery disease.
Biochemical and biophysical research communications - 17 Jan 2014
Gu Xiao-Long, Ma Na, Xiang Ding-Cheng, Huang Jun, Dong Zheng-Hua, Lei Hui-Yan, Ding Ru, Gong Zhi-Hua, Wen Yan-Fei, Qiu Jian, Ma Lan
Abstract excerpt
Stromal cell-derived factor-1 (SDF-1) plays critical roles in vascular development and hematopoiesis. Here, we investigated the function of SDF-1 rs1801157G/A polymorphism in various immune cells and examined its association with susceptibility to coronary artery disease (CAD). Protein and mRNA levels of SDF-1 were tested in peripheral CD4+ T cell, CD8+ T cells, monocytes, and natural killer (NK) T cells from...
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