Article
A pilot study of early onset obsessive-compulsive disorder: Symptom dimensions and association analysis with polymorphisms of the serotonin transporter gene.
Psychiatry research - 1 Oct 2018
Kenezloi Eszter, Lakatos Krisztina, Horvath Erzsebet Zsofia, Sasvari-Szekely Maria, Nemoda Zsofia
Abstract excerpt
Our aim was to introduce more homogenous phenotypes for studying genetic variations in the clinically heterogeneous obsessive compulsive disorder (OCD) beside classical case-control analysis. Symptoms were assessed with Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS), and principle component analysis of the lifetime symptom categories yielded four factors (Cleaning, Obsessive, Compulsive, Sexual). The...
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