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Article

Exploring genetic variants in obsessive compulsive disorder severity: A GWAS approach.

Journal of affective disorders - 15 Apr 2020

Alemany-Navarro María, Cruz Raquel, Real Eva, Segalàs Cinto, Bertolín Sara, Baenas Isabel, Domènech Laura, Rabionet Raquel, Carracedo Ángel, Menchón Jose M, Alonso Pino

Abstract excerpt

BACKGROUND: The severity of Obsessive-Compulsive Disorder (OCD) varies significantly among probands. No study has specifically investigated the genetic base of OCD severity. A previous study from our group found an OCD polygenic risk score to predict pre- and post-treatment severity. This study explores the genomic bases of OCD severity. METHODS: We administered the Yale-Brown Obsessive Compulsive Scale (Y-BOCS)...

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PMID: 32063569
DOI: 10.1016/j.jad.2020.01.161

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