Article
Exploratory factor analysis of obsessive-compulsive patients and association with 5-HTTLPR polymorphism.
American journal of medical genetics - 8 Apr 2002
Cavallini Maria Cristina, Di Bella Daniela, Siliprandi Francesca, Malchiodi Francesca, Bellodi Laura
Abstract excerpt
The determination of a genetic basis for obsessive-compulsive disorder (OCD) depends on how phenotypic boundaries are defined. Although a hypothesis for serotonin dysfunction in OCD has been advanced, no genes specifically responsible for serotonin regulation have as yet been definitively related to the etiology of OCD. The phenotypic variability of OCD could be at the basis of the failure of molecular biology...
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