Article
A revisit of the conformational dynamics of SNARE protein rYkt6.
Biochemical and biophysical research communications - 18 Sept 2018
Wu Shaowen, Wang Dongdong, Weng Jingwei, Liu Jianwei, Wang Wenning
Abstract excerpt
N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins are involved in the fusion of vesicles with their target membranes. R-SNARE protein Ykt6 is one of the most conserved SNARE in eukaryotes. The conformational state of Ykt6 is regulated by the lipidations at its C-terminal motif. Previous studies show that the binding of dodecylphosphocholine (DPC) can stabilize a closed conformation of...
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