Article
Association between KIR genotypes and HLA-B alleles on viral load in Southern Brazilian individuals infected by HIV-1 subtypes B and C.
Human immunology - 1 Oct 2016
Fernandes-Cardoso Juliana, Süffert Theodoro Armando, Correa Maria da Gloria, Jobim Luiz Fernando Job, Jobim Mariana, Salim Patricia Hartstein, Arruda Monica Barcelos, Boullosa Lidia Theodoro, Tanuri Amilcar, Porto Luis Cristóvão, Ferreira Orlando C
Abstract excerpt
There is a great variety of HIV-1 subtypes circulating in Brazil, including subtype C, whose prevalence is on the rise, particularly in the southern region. Many host and viral genetic factors may be involved in this trend. We evaluated the influence of human leukocyte antigen (HLA) class I alleles and killer-cell immunoglobulin-like receptor (KIR) genotypes on viral set point and T-CD4(+) parameters in 84...
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