Article
HLA-C Single Nucleotide Polymorphism Associated with Increased Viral Load Level in HIV-1 Infected Individuals from Northeast Brazil.
Current HIV research - 1 Jan 2017
Celerino da Silva Ronaldo, Moura Ronald Rodrigues, Victor Campos Coelho Antonio, Arraes Luiz Cláudio, Brandão Lucas André Cavalcanti, Crovella Sergio, Lima Guimarães Rafael
Abstract excerpt
BACKGROUND: Genetic variations in Human leukocyte antigen C (HLA-C), Zinc ribbon domain containing 1 (ZNRD1) and its antisense RNA (ZNRD1-AS1) genes are known to influence the HIV-1 replication and disease progression. OBJECTIVE AND METHOD: We evaluated the distribution of HLA-C (rs10484554, rs9264942) and ZNRD1 (rs8321) and ZNRD1-AS1 (rs3869068), single nucleotide polymorphisms (SNPs) in 266 HIV-1-infected and...
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