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Article

Genetic polymorphisms in the C19orf66 gene influenced HIV-1 infection in a Yunnan population.

PeerJ - 1 Jan 2023

Zhang Yaxiang, Feng Yue, Liu Yang, Liu Li, Xia Xueshan, Zhang A-Mei

Abstract excerpt

Background: Due to the deficiencies of vaccines and effective medicine, the human immunodeficiency virus (HIV) infection mechanism should be studied. The C19orf66 gene, one of the interferon-stimulated genes (ISGs), expresses broad-spectra anti-viral activity, including inhibiting HIV replication. Methods: In this study, we collect 421 HIV-1 infected patients and 448 controls to genotype three SNPs in the...

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Identifiers

PMID: 37701839
DOI: 10.7717/peerj.16005
PMCID: PMC10493081

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