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Article

Characterization of Factors Affecting the Detection Limit of EGFR p.T790M in Circulating Tumor DNA.

Technology in cancer research & treatment - 1 Jan 2018

Fahoum Ibrahim, Forer Relly, Volodarsky Dina, Vulih Inna, Bick Tova, Sarji Shada, Bamberger Zeev, Ben-Izhak Ofer, Sabo Edmond, Hershberg Ruth, Hershkovitz Dov

Abstract excerpt

OBJECTIVE: Circulating tumor DNA is a promising noninvasive tool for cancer monitoring. One of the challenges in applying this tool is the detection of low-frequency mutations. The detection limit of these mutations varies between different molecular methods. The aim of this study is to characterize the factors affecting the limit of detection for epidermal growth factor receptor p.T790M mutation in circulating...

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Identifiers

PMID: 30099961
DOI: 10.1177/1533033818793653
PMCID: PMC6090485

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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