Article
Comparison of Target Enrichment Platforms for Circulating Tumor DNA Detection.
Scientific reports - 5 Mar 2020
Lam So Ngo, Zhou Ying Chun, Chan Yee Man, Foo Ching Man, Lee Po Yi, Mok Wing Yeung, Wong Wing Sum, Fung Yan Yee, Wong Kit Yee, Huang Jun Yuan, Chow Chun Kin
Abstract excerpt
Cancer-related mortality of solid tumors remains the major cause of death worldwide. Circulating tumor DNA (ctDNA) released from cancer cells harbors specific somatic mutations. Sequencing ctDNA opens opportunities to non-invasive population screening and lays foundations for personalized therapy. In this study, two commercially available platforms, Roche's Avenio ctDNA Expanded panel and QIAgen's QIAseq Human...
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