Article
Analytical evaluation of circulating tumor DNA sequencing assays.
Scientific reports - 29 Feb 2024
Li Wenjin, Huang Xiayu, Patel Rajesh, Schleifman Erica, Fu Shijing, Shames David S, Zhang Jingyu
Abstract excerpt
In China, circulating tumor DNA analysis is widely used and numerous assays are available. Systematic evaluation to help users make informed selections is needed. Nine circulating tumor DNA assays, including one benchmark assay, were evaluated using 23 contrived reference samples. There were two sample types (cell-free DNA and plasma samples), three circulating tumor DNA inputs (low, < 20 ng; medium, 20-50 ng;...
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