Article
Detection of EGFR Variants in Plasma: A Multilaboratory Comparison of a Real-Time PCR EGFR Mutation Test in Europe.
The Journal of molecular diagnostics : JMD - 1 Jul 2018
Keppens Cleo, Palma John F, Das Partha M, Scudder Sidney, Wen Wei, Normanno Nicola, van Krieken J Han, Sacco Alessandra, Fenizia Francesca, Gonzalez de Castro David, Hönigschnabl Selma, Kern Izidor, Lopez-Rios Fernando, Lozano Maria D, Marchetti Antonio, Halfon Philippe, Schuuring Ed, Setinek Ulrike, Sorensen Boe, Taniere Phillipe, Tiemann Markus, Vosmikova Hana, Dequeker Elisabeth M C
Abstract excerpt
Molecular testing of EGFR is required to predict the response likelihood to targeted therapy in non-small cell lung cancer. Analysis of circulating tumor DNA in plasma may complement limitations of tumor tissue. This study evaluated the interlaboratory performance and reproducibility of a real-time PCR EGFR mutation test (cobas EGFR Mutation Test v2) to detect EGFR variants in plasma. Fourteen laboratories...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.