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Plasma ctDNA enhances the tissue-based detection of oncodriver mutations in colorectal cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Aug 2024

Wang Wei, Huang Yisen, Kong Jianqiao, Lu Lin, Liao Qianxiu, Zhu Jingtao, Wang Tinghao, Yan Linghua, Dai Min, Chen Zhan, You Jun

Abstract excerpt

PURPOSE: The advent of circulating tumor DNA (ctDNA) technology has provided a convenient and noninvasive means to continuously monitor cancer genomic data, facilitating personalized cancer treatment. This study aimed to evaluate the supplementary benefits of plasma ctDNA alongside traditional tissue-based next-generation sequencing (NGS) in identifying targetable mutations and tumor mutational burden (TMB) in...

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Adenomatous Polyposis Coli Protein
Circulating Tumor DNA
Class I Phosphatidylinositol 3-Kinases
Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

GTP Phosphohydrolases

Proto-Oncogene Proteins B-raf

Proto-Oncogene Proteins p21(ras)

Receptor, ErbB-2

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Open in PubMed Open full text

Identifiers

PMID: 38777950
DOI: 10.1007/s12094-024-03422-7
PMCID: PMC11249419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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