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Role of lipoprotein (a) and LPA KIV2 repeat polymorphism in bicuspid aortic valve stenosis and calcification: a proof of concept study.

Internal and emergency medicine - 1 Jan 2019

Sticchi Elena, Giusti Betti, Cordisco Antonella, Gori Anna Maria, Sereni Alice, Sofi Francesco, Mori Fabio, Colonna Stefania, Fugazzaro Maria Pia, Pepe Guglielmina, Nistri Stefano, Marcucci Rossella

Abstract excerpt

Hemodynamic valvular impairment is a frequent determinant of the natural history of bicuspid aortic valve (BAV). The role of elevated Lp(a) levels and LPA Kringle IV type 2 (KIV-2) size polymorphism in influencing aortic valve calcification and stenosis development in patients with tricuspid aortic valve was recognized. In this study, we investigate the association between Lp(a) and LPA KIV-2 repeat number, and...

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Identifiers

PMID: 30099661
DOI: 10.1007/s11739-018-1925-8

Genes

LPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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